Nowadays, Green Supply Chain (GSC) networks are developed as essential components in the commerce strategy. Producing green products is an instance of environmental achievements worldwide, such that ecological statistics show that consumers avoid buying products that emit pollution during production. Therefore, pursuing sustainability approaches in Supply Chain Management (SCM) turns into a fundamental issue. In the present article, we discuss the role of supply chain integration on the environment using Knowledge Combination (KC), Green Innovation (GI), and the mediating role of reactive and Proactive Dimensions (PDs) of resilience. The current study is a quantitative descriptive-correlational research with an applied purpose. The research population analysis is available to experts in the supply chain field. The research findings are expressed in the variance-based structural equation approach and the Radial Basis Function (RBF) neural network approach. Accordingly, supplier integration improves resilience and environmental performance by employing knowledge synthesis. Innovation moderates environmental performance and supplier integration. The results illustrate that reactive and preventive dimensions of Supply Chain Resilience (SCR) have a decisive role in environmental performance.